Prep your vehicle.
At minimum you need an ice scraper and a snow brush. I love the combination ones, like this model. Note to Southerners: You need to brush off the entire car, including the trunk, hood and roof; I know this is not necessarily common knowledge.
If you live somewhere with extreme weather, it's time to dig out those snow tires. You should also keep an emergency kit in the car, complete with bottled water, energy bars, blankets and a flashlight. Be sure you have your phone charged and with you when you're traveling during the winter. A bag of sand in the trunk will come in handy if you get stuck.
If you can afford the luxury of having your driveway plowed, call your snowplow person and make sure you're good to go for that first storm.